RP-HPLC Method Development and Validation for Determination of Didanosine in Pharmaceutical Dosage Forms
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چکیده
منابع مشابه
RP-HPLC method development and validation for determination of eptifibatide acetate in bulk drug substance and pharmaceutical dosage forms
A new, rapid, economical and isocratic reverse phase high performance liquid chromatography (RP-HPLC) method was developed for the determination of eptifibatide acetate, a small synthetic antiplatelet peptide, in bulk drug substance and pharmaceutical dosage forms. The developed method was validated as per of ICH guidelines. The chromatographic separation was achieved isocratically on C18 colum...
متن کاملRP-HPLC method development and validation for determination of eptifibatide acetate in bulk drug substance and pharmaceutical dosage forms
A new, rapid, economical and isocratic reverse phase high performance liquid chromatography (RP-HPLC) method was developed for the determination of eptifibatide acetate, a small synthetic antiplatelet peptide, in bulk drug substance and pharmaceutical dosage forms. The developed method was validated as per of ICH guidelines. The chromatographic separation was achieved isocratically on C18 colum...
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A rapid, linear, precise, selective and accurate reverse phase HPLC method was developed and validated for simultaneous estimation of glibenclamide in tablet dosage form. The method employed for analysis using methanol as a solvent. The wavelength UV 300 nm was selected for estimation and linearity was observed in the concentration range of 160 240 μg/ml for glibenclamide respectively. The reco...
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Rivaroxaban, an anti-clotting medication, acts at a crucial point in the blood-clotting process and stops the formation of blood clots. In this study, RP-HPLC method was developed for the determination of rivaroxaban in tablets (Xarelto® (10 mg)). Phenomenex Luna 5 μm C18 100 Å LC Column (250 x 4.6 mm) was used at 40 oC. Isocratic elution was performed with ACN:Water (55:45 v/v) mixture. The fl...
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This study describes development and subsequent validation of a reversed phase high performance liquid chromatographic (RPHPLC) method for the estimation of ursodeoxycholic acid used to solubilize cholesterol gallstones, in conventional tablet dosage formulation and in prepared dosage form. The chromatographic system was achieved in a BDS Hypersil C8 column (Thermo, 250mm x 4.6 mm, 5 μ) with an...
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ژورنال
عنوان ژورنال: Journal of Drug Delivery and Therapeutics
سال: 2019
ISSN: 2250-1177
DOI: 10.22270/jddt.v9i4-s.3328